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Kisspeptin-10 is a synthetic peptide that mimics the natural neuropeptide known as kisspeptin. This compound plays a crucial role in regulating the hypothalamic-pituitary-gonadal (HPG) axis, directly influencing the release of gonadotropin-releasing hormone (GnRH). As a result, Kisspeptin-10 has become a key area of interest in reproductive health, hormone therapy, and research-based enhancement protocols.
Researchers and clinicians alike explore Kisspeptin-10 for its ability to:
The increasing interest in Kisspeptin-10 stems from its selective role in stimulating the HPG axis without affecting other hormonal pathways, reducing the risk of off-target effects. Researchers are actively studying its use for:
Fertility restoration: Especially in men with idiopathic infertility or suppressed gonadotropin levels.
Pubertal delay treatment: Particularly in adolescents with delayed sexual maturation.
Alternative to traditional hormone therapies: Offering a more physiological approach to boosting endogenous hormone levels.
Kisspeptin-10 binds to the GPR54 receptor, which is located in the hypothalamus. Upon binding, it stimulates the release of GnRH, triggering downstream secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland.
Typical research dosing protocols use Kisspeptin-10 in microgram quantities. Although human dosing has not been FDA-approved, animal model protocols often range from:
50mcg to 100mcg per administration, subcutaneously
Frequency: Daily or every other day for 2–4 weeks depending on the hypothesis under investigation
Note: Kisspeptin-10 is strictly intended for laboratory research and not for human consumption.
When searching for a reputable source to buy Kisspeptin-10, prioritize the following:
Purity Level: Minimum 98% purity, verified by COA (Certificate of Analysis)
Storage: Lyophilized powder should be stored at -20°C and reconstituted with bacteriostatic water.
Vendor Reputation: Ensure the supplier has transparent third-party lab testing and GMP manufacturing practices.
Shipping Conditions: The peptide must be shipped with cold packs to preserve integrity during transit.
Feature Low-Quality Vendors High-Quality Vendors
Peptide Purity Below 95% 98% or higher
COA Provided Often missing Always included
Third-Party Testing Rare Standard
Cold Chain Shipping Optional or absent Mandatory with ice packs
Customer Support Generic and delayed Responsive and knowledgeable
In rodent and primate studies, Kisspeptin-10 is generally well-tolerated. However, researchers have observed:
These effects are often dose-dependent and typically resolve without intervention.
Proper storage ensures peptide integrity and experiment reproducibility:
The demand for Kisspeptin-10 has surged, but so have counterfeit or low-grade products. Always purchase from suppliers who:
If you're ready to buy Kisspeptin-10, ensure you're sourcing it from a scientifically reputable vendor that adheres to high standards of peptide production, verification, and delivery. Quality and storage are non-negotiable when it comes to biological research. Kisspeptin-10 continues to open new frontiers in reproductive and hormonal studies—make sure your research isn't held back by substandard compounds.